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COVID-19 疫苗接种对人类生育力的影响:后疫情时代文献综述。

Effects of COVID-19 vaccination on human fertility: a post-pandemic literature review.

机构信息

Department of Obstetrics and Gynecology, the First Affiliated Hospital of Anhui Medical University, Hefei, China.

Department of General Office, the First Affiliated Hospital of Anhui Medical University, Hefei, China.

出版信息

Ann Med. 2023 Dec;55(2):2261964. doi: 10.1080/07853890.2023.2261964. Epub 2023 Sep 27.

Abstract

Although vaccination with the Coronavirus disease 2019 vaccine is important and effective in the prevention of SARS-CoV-2 infection, the public expressed concerns regarding the adverse effects of vaccine on fertility. Some reviews have focused on it, they have been unable to collect sufficient research data because of the earlier publication period. As relevant evidence has gradually increased, we reviewed these studies from the perspectives of males, females with or without pregnancy, and different vaccine types. The results suggest that although males may experience fluctuations in semen parameters within their physiological ranges after receiving the vaccine, it has not yet reached a level of influence on the partner's pregnancy probability. As to female without pregnancy, it is believed that vaccination will not affect fertility; however, more research is needed to explore the short-term impact. Vaccination during any trimester is considered safe in pregnant women.

摘要

尽管接种 2019 年冠状病毒病疫苗对于预防 SARS-CoV-2 感染非常重要且有效,但公众对疫苗对生育能力的不良影响表示担忧。一些综述对此进行了关注,但由于发表时间较早,未能收集到足够的研究数据。随着相关证据的逐渐增加,我们从男性、有或没有怀孕的女性以及不同类型的疫苗等角度对这些研究进行了回顾。结果表明,尽管男性在接种疫苗后其精液参数可能在生理范围内出现波动,但尚未达到影响伴侣妊娠概率的程度。至于未怀孕的女性,据信接种疫苗不会影响生育能力;然而,需要进一步研究来探索短期影响。在孕妇的任何孕期接种疫苗都被认为是安全的。

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