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牛磺酸在衰老和心血管健康中的功能作用:最新综述。

Functional Role of Taurine in Aging and Cardiovascular Health: An Updated Overview.

机构信息

Department of Medicine, Fleischer Institute for Diabetes and Metabolism (FIDAM), Einstein-Mount Sinai Diabetes Research Center (ES-DRC), Einstein Institute for Aging Research, Albert Einstein College of Medicine, New York, NY 10461, USA.

Department of Molecular Pharmacology, Division of Cardiology, Wilf Family Cardiovascular Research Institute, Albert Einstein College of Medicine, New York, NY 10461, USA.

出版信息

Nutrients. 2023 Sep 30;15(19):4236. doi: 10.3390/nu15194236.

Abstract

Taurine, a naturally occurring sulfur-containing amino acid, has attracted significant attention in recent years due to its potential health benefits. Found in various foods and often used in energy drinks and supplements, taurine has been studied extensively to understand its impact on human physiology. Determining its exact functional roles represents a complex and multifaceted topic. We provide an overview of the scientific literature and present an analysis of the effects of taurine on various aspects of human health, focusing on aging and cardiovascular pathophysiology, but also including athletic performance, metabolic regulation, and neurological function. Additionally, our report summarizes the current recommendations for taurine intake and addresses potential safety concerns. Evidence from both human and animal studies indicates that taurine may have beneficial cardiovascular effects, including blood pressure regulation, improved cardiac fitness, and enhanced vascular health. Its mechanisms of action and antioxidant properties make it also an intriguing candidate for potential anti-aging strategies.

摘要

牛磺酸是一种天然存在的含硫氨基酸,近年来因其潜在的健康益处而受到广泛关注。牛磺酸存在于各种食物中,常用于能量饮料和补品中,其对人体生理学的影响已被广泛研究。确定其确切的功能作用是一个复杂和多方面的课题。我们提供了科学文献的概述,并对牛磺酸对人类健康各个方面的影响进行了分析,重点关注衰老和心血管病理生理学,但也包括运动表现、代谢调节和神经功能。此外,我们的报告总结了牛磺酸摄入的当前建议,并讨论了潜在的安全问题。来自人体和动物研究的证据表明,牛磺酸可能对心血管系统有有益的影响,包括血压调节、改善心脏健康和增强血管健康。其作用机制和抗氧化特性使其成为潜在抗衰老策略的一个有趣候选者。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4add/10574552/b314f261fdbc/nutrients-15-04236-g001.jpg

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