Department of Cardiology, Renmin Hospital of Wuhan University, Jiefang Road 238, Wuhan, 430060, People's Republic of China.
Hubei Key Laboratory of Metabolic and Chronic Diseases, Wuhan, 430060, People's Republic of China.
J Cardiovasc Transl Res. 2024 Apr;17(2):322-333. doi: 10.1007/s12265-023-10442-1. Epub 2023 Oct 17.
With increased ageing of the population, cardiovascular disease (CVD) has become the most important factor endangering human health worldwide. Although the treatment of CVD has become increasingly advanced, there are still a considerable number of patients with conditions that have not improved. According to the latest clinical guidelines of the European Cardiovascular Association, obesity has become an independent risk factor for CVD. Adipose tissue includes visceral adipose tissue and subcutaneous adipose tissue. Many previous studies have focused on subcutaneous adipose tissue, but visceral adipose tissue has been rarely studied. However, as a type of visceral adipose tissue, epicardial adipose tissue (EAT) has attracted the attention of researchers because of its unique anatomical and physiological characteristics. This review will systematically describe the physiological characteristics and evaluation methods of EAT and emphasize the important role and treatment measures of EAT in CVD.
随着人口老龄化的加剧,心血管疾病(CVD)已成为全球范围内危害人类健康的最重要因素。尽管 CVD 的治疗方法已经越来越先进,但仍有相当数量的患者病情没有改善。根据欧洲心血管协会的最新临床指南,肥胖已成为 CVD 的一个独立危险因素。脂肪组织包括内脏脂肪组织和皮下脂肪组织。许多先前的研究都集中在皮下脂肪组织上,但内脏脂肪组织很少被研究。然而,作为一种内脏脂肪组织,心外膜脂肪组织(EAT)因其独特的解剖和生理特性引起了研究人员的关注。本综述将系统地描述 EAT 的生理特征和评估方法,并强调 EAT 在 CVD 中的重要作用和治疗措施。