人参皂苷 Rg3：抗癌机制及其潜在治疗应用的综述。
Ginsenoside Rg3: A Review of its Anticancer Mechanisms and Potential Therapeutic Applications.
机构信息
Core Facility of West China Hospital, Sichuan University, Chengdu, 610041, China.
NHC Key Laboratory of Transplant Engineering and Immunology, Frontier Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu, China.
出版信息
Curr Top Med Chem. 2024;24(10):869-884. doi: 10.2174/0115680266283661240226052054.
BACKGROUND
Traditional Chinese Medicine (TCM) has a long history of treating various diseases and is increasingly being recognized as a complementary therapy for cancer. A promising natural compound extracted from the Chinese herb ginseng is ginsenoside Rg3, which has demonstrated significant anticancer effects. It has been tested in a variety of cancers and tumors and has proven to be effective in suppressing cancer.
OBJECTIVES
This work covers various aspects of the role of ginsenoside Rg3 in cancer treatment, including its biological functions, key pathways, epigenetics, and potential for combination therapies, all of which have been extensively researched and elucidated. The study aims to provide a reference for future research on ginsenoside Rg3 as an anticancer agent and a support for the potential application of ginsenoside Rg3 in cancer treatment.
背景
中医药（TCM）在治疗各种疾病方面有着悠久的历史，并且越来越被视为癌症的一种补充疗法。从中药人参中提取的一种有前途的天然化合物是人参皂苷 Rg3，它已被证明具有显著的抗癌作用。它已在各种癌症和肿瘤中进行了测试，并已被证明能有效抑制癌症。
目的
这项工作涵盖了人参皂苷 Rg3 在癌症治疗中的各种作用，包括其生物学功能、关键途径、表观遗传学以及与联合治疗的潜力，所有这些都已经得到了广泛的研究和阐明。该研究旨在为未来研究人参皂苷 Rg3 作为抗癌剂提供参考，并为人参皂苷 Rg3 在癌症治疗中的潜在应用提供支持。
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