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人类肠道微生物群、饮食与精神障碍。

Human gut microbiome, diet, and mental disorders.

作者信息

Borrego-Ruiz Alejandro, Borrego Juan J

机构信息

Departamento de Psicología Social y de las Organizaciones, Universidad Nacional de Educación a Distancia (UNED), Madrid, Spain.

Departamento de Microbiología, Universidad de Málaga. Instituto de Investigación Biomédica de Málaga y Plataforma en Nanomedicina BIONAND, Málaga, Spain.

出版信息

Int Microbiol. 2025 Jan;28(1):1-15. doi: 10.1007/s10123-024-00518-6. Epub 2024 Apr 1.

Abstract

Diet is one of the most important external factor shaping the composition and metabolic activities of the gut microbiome. The gut microbiome plays a crucial role in host health, including immune system development, nutrients metabolism, and the synthesis of bioactive molecules. In addition, the gut microbiome has been described as critical for the development of several mental disorders. Nutritional psychiatry is an emerging field of research that may provide a link between diet, microbial function, and brain health. In this study, we have reviewed the influence of different diet types, such as Western, Mediterranean, vegetarian, and ketogenic, on the gut microbiota composition and function, and their implication in various neuropsychiatric and psychological disorders.

摘要

饮食是塑造肠道微生物群组成和代谢活动的最重要外部因素之一。肠道微生物群在宿主健康中起着至关重要的作用,包括免疫系统发育、营养物质代谢以及生物活性分子的合成。此外,肠道微生物群已被描述为几种精神障碍发展的关键因素。营养精神病学是一个新兴的研究领域,可能为饮食、微生物功能和大脑健康之间提供联系。在本研究中,我们综述了不同饮食类型,如西方饮食、地中海饮食、素食和生酮饮食,对肠道微生物群组成和功能的影响,以及它们在各种神经精神和心理障碍中的作用。

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