Novel Thiourea-Based Chemosensor for Ultrasensitive and Selective Detection of Hg.

We have successfully developed a novel thiourea-based chemosensorN-((6-methylbenzo[d]thiazol-2-yl)carbamothioyl)-3,5-bis(trifluoromethyl)benzamide, TS, specifically designed for the detection of Hg. The structure of TS was comprehensively characterized using techniques such as H NMR, FT-IR, and fluorescence spectroscopy. TS exhibited exceptional fluorescence enhancement in the presence of Hg ions when tested against a broad range of metal ions, including Cr, Co, Ca, Na, Pb, Mn, K, Ni, Mg, Zn, Cd, Cu, Ag, and Al. The selectivity and sensitivity studies were performed in a MeOH/water (2:98, v/v) solvent system, where TS demonstrated a highly sensitive response to Hg ions with a detection limit as low as 0.005 µg/mL. Insights into the sensing mechanism were explained through fluorescence and Job's plot analysis, confirming a robust and efficient detection pathway with a 2:1 binding mode between TS and Hg. To assess its real-world applicability, recovery experiments were conducted on environmental and agricultural samples spiked with Hg ions. The chemosensor achieved impressive recovery rates ranging from 90.0 ± 0.24% to 102.0 ± 0.58% across various concentration levels, demonstrating its accuracy and reliability. The unique attributes of TS, including its cost-effectiveness, simplicity, high selectivity, and ultra-sensitivity, make it an excellent candidate for the detection of trace levels of Hg in diverse applications.