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1990年至2021年育龄妇女全球、区域和国家的腰痛负担:基于2021年全球疾病负担研究的分析

Global, regional, and national burdens of low back pain in women of childbearing age from 1990 to 2021: an analysis based on the global burden of disease study 2021.

作者信息

Zhang Shiwen, Ma Xuan, Yao Yao, Pan Huashan, Zou Lijuan

机构信息

Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, 510006, China.

The Eighth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, 518033, China.

出版信息

BMC Public Health. 2025 Feb 7;25(1):515. doi: 10.1186/s12889-025-21659-x.

Abstract

BACKGROUND

Low back pain (LBP) is very common in women of child bearing age (WCBA) and is a major burden on individuals and society, but studies about it have not been reported.

METHODS

Trend analyses were based on data from the Global Burden of Disease, Injuries, and Risk Factors Study (GBD) 2021. We investigated global trends in the number of prevalence cases, prevalence and the years lived with disability (YLDs), and the YLDs rate for LBP in the WCBA. We used joint point regression analyses to report average annual changes and identify the most variable years in the global trend. Simultaneously, we further analyzed these trends by stratifying them by the region, nation, and age.

RESULTS

Globally, the number of the prevalence and the YLDs for LBP increased substantially from 1990 to 2021(the prevalence: 39.65%) (the YLDs: 39.53%), whereas the prevalence and the YLDs rate of WCBA LBP decreased (the prevalence: AAPC: -0.1355 [95% CI -0.1419 to -0.1288) (the YLDs: AAPC: -0.1365 [95% CI -0.1427 to -0.1302]). Regionally, the prevalence and the YLDs rate of LBP among WCBA in the medium socio-demographic index region showed an increasing trend(the prevalence: AAPC: 0.1291 [95% CI: 0.118 to 0.1396]) (the YLDs: AAPC: 0.1371 [95% CI: 0.1251 to 0.1499]). Nationally, Thailand and Vietnam were the countries with the largest increases in YLD rates(Thailand: AAPC: 0.7742 [95% CI: 0.7589 to 0.7904]) (Vietnam: AAPC: 0.7364 [95% CI: 0.7263 to 0.7468]). In age patterns, the highest prevalence and YLDs rates of LBP were found among women in the 45-49 age group(the prevalence: 14,412.77 per 100,000 in 2021 [95% UI: 10,482.27 to 19,077.3]) (the YLDs: 1,639.56 per 100,000 population (95% UI: 1,035.24 to 2,494.9]).

CONCLUSION

Despite declines in the prevalence and YLDs of WCBA LBP, the burden remains high. Age- and region-specific prevention and healthcare strategies should be optimized to meet the needs of WCBA and reduce the burden of disease.

摘要

背景

下背痛(LBP)在育龄女性(WCBA)中非常常见,是个人和社会的重大负担,但关于它的研究尚未见报道。

方法

趋势分析基于2021年全球疾病、伤害及风险因素负担研究(GBD)的数据。我们调查了WCBA中LBP的患病率病例数、患病率和残疾生存年数(YLDs)以及YLDs率的全球趋势。我们使用联合点回归分析来报告平均年度变化并确定全球趋势中变化最大的年份。同时,我们按地区、国家和年龄对这些趋势进行分层,进一步分析这些趋势。

结果

在全球范围内,1990年至2021年期间,LBP的患病率和YLDs大幅增加(患病率:39.65%)(YLDs:39.53%),而WCBA的LBP患病率和YLDs率下降(患病率:平均年度百分比变化(AAPC):-0.1355 [95%置信区间-0.1419至-0.1288])(YLDs:AAPC:-0.1365 [95%置信区间-0.1427至-0.1302])。在区域方面,中等社会人口指数区域的WCBA中LBP的患病率和YLDs率呈上升趋势(患病率:AAPC:0.1291 [95%置信区间:0.118至0.1396])(YLDs:AAPC:0.1371 [95%置信区间:0.1251至0.1499])。在国家层面,泰国和越南是YLDs率增幅最大的国家(泰国:AAPC:0.7742 [95%置信区间:0.7589至0.7904])(越南:AAPC:0.7364 [95%置信区间:0.7263至0.7468])。在年龄模式方面,45-49岁年龄组的女性中LBP的患病率和YLDs率最高(患病率:2021年每10万人中14412.77例[95%不确定区间:10482.27至19077.3])(YLDs:每10万人口中1639.56例(95%不确定区间:1035.24至2494.9])。

结论

尽管WCBA的LBP患病率和YLDs有所下降,但负担仍然很高。应优化针对特定年龄和地区的预防及医疗保健策略,以满足WCBA的需求并减轻疾病负担。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8eb7/11806660/22d33e4ebd98/12889_2025_21659_Fig1_HTML.jpg

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