CSIRO Australian Animal Health Laboratory, Geelong, Victoria 3220, Australia.
Curr Opin Virol. 2013 Feb;3(1):84-91. doi: 10.1016/j.coviro.2012.11.006. Epub 2012 Dec 21.
Bats are being increasingly recognized as an important reservoir of zoonotic viruses of different families, including SARS coronavirus, Nipah virus, Hendra virus and Ebola virus. Several recent studies hypothesized that bats, an ancient group of flying mammals, are the major reservoir of several important RNA virus families from which other mammalian viruses of livestock and humans were derived. Although this hypothesis needs further investigation, the premise that bats carry a large number of viruses is commonly accepted. The question of whether bats have unique biological features making them ideal reservoir hosts has been the subject of several recent reviews. In this review, we will focus on the public health implications of bat derived zoonotic viral disease outbreaks, examine the drivers and risk factors of past disease outbreaks and outline research directions for better control of future disease events.
蝙蝠正日益被认为是不同科属的人畜共患病病毒的重要贮存宿主,包括 SARS 冠状病毒、尼帕病毒、亨德拉病毒和埃博拉病毒。一些最近的研究假设,蝙蝠作为一种古老的飞行哺乳动物,是几种重要的 RNA 病毒科属的主要贮存宿主,而其他家畜和人类的哺乳动物病毒正是从这些病毒中衍生而来。尽管这一假设需要进一步研究,但蝙蝠携带大量病毒这一前提是普遍被接受的。蝙蝠是否具有使其成为理想贮存宿主的独特生物学特征这一问题,是最近几次综述的主题。在这篇综述中,我们将重点关注蝙蝠源性人畜共患病病毒病暴发的公共卫生意义,探讨过去疾病暴发的驱动因素和风险因素,并概述未来更好控制疾病事件的研究方向。