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一种用于快速、特异性检测痕量生物SO2衍生物及生物成像应用的扭曲分子内电荷转移探针。

A twisted intramolecular charge transfer probe for rapid and specific detection of trace biological SO2 derivatives and bio-imaging applications.

作者信息

Zhu Leiming, Xu Junchao, Sun Zhe, Fu Boqiao, Qin Caiqin, Zeng Lintao, Hu Xichao

机构信息

School of Chemistry & Chemical Engineering, Tianjin University of Technology, Tianjin 300384, P.R. China.

出版信息

Chem Commun (Camb). 2015 Jan 21;51(6):1154-6. doi: 10.1039/c4cc08258c.

Abstract

We reported a reactive probe for HSO3(-), which showed a colorimetric and ratiometric fluorescence response to HSO3(-) with fast response (t1/2 = 20 s), good specificity and low detection limit (3.0 nM). The probe was cell membrane permeable and successfully used for visualizing trace SO2 derivatives in living cells.

摘要

我们报道了一种用于HSO3(-)的反应性探针,它对HSO3(-)表现出比色和比率荧光响应,响应迅速(t1/2 = 20秒),特异性良好且检测限低(3.0 nM)。该探针具有细胞膜通透性,并成功用于可视化活细胞中的痕量SO2衍生物。

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