Department of Chemistry, Rajalakshmi Engineering College, Chennai, 602105, India.
J Fluoresc. 2020 Sep;30(5):1203-1223. doi: 10.1007/s10895-020-02570-7. Epub 2020 Jul 31.
Fluorescent determinations of analytes have proven to be a powerful method due to their simplicity, low cost, detection limit, rapid photoluminescence response, and applicability to bioimaging. Fluorescence imaging as a powerful tool for monitoring biomolecules within the living systems. Schiff base has been extensively used as strongly absorbing and colorful chromophores in the design of chemosensors. In recent years, Schiff base based fluorescent probes have been developed for the detection of various toxic analytes and imaging of various analytes in biological systems. This review gives an overview of the important fluorescent sensors which are based on Schiff base, their approaches for molecular recognition, and their potential application in bioimaging studies.
荧光分析法由于其简单、低成本、检测限低、快速光致发光响应以及适用于生物成像等优点,已被证明是一种强大的方法。荧光成像作为监测活系统内生物分子的有力工具。席夫碱在设计化学传感器中被广泛用作强吸收和多彩的生色团。近年来,基于席夫碱的荧光探针已被开发用于检测各种有毒分析物,并对生物系统中的各种分析物进行成像。本综述概述了基于席夫碱的重要荧光传感器,它们的分子识别方法以及它们在生物成像研究中的潜在应用。