MMWR Morb Mortal Wkly Rep. 2021 Oct 29;70(43):1495-1500. doi: 10.15585/mmwr.mm7043a1.
Endorsed by the World Health Assembly in 2020, the Immunization Agenda 2030 (IA2030) strives to reduce morbidity and mortality from vaccine-preventable diseases across the life course (1). This report, which updates a previous report (2), presents global, regional,* and national vaccination coverage estimates and trends as of 2020. Changes are described in vaccination coverage and the numbers of unvaccinated and undervaccinated children as measured by receipt of the first and third doses of diphtheria, tetanus, and pertussis-containing vaccine (DTP) in 2020, when the COVID-19 pandemic began, compared with 2019. Global estimates of coverage with the third dose of DTP (DTP3) and a polio vaccine (Pol3) decreased from 86% in 2019 to 83% in 2020. Similarly, coverage with the first dose of measles-containing vaccine (MCV1) dropped from 86% in 2019 to 84% in 2020. The last year that coverage estimates were at 2020 levels was 2009 for DTP3 and 2014 for both MCV1 and Pol3. Worldwide, 22.7 million children (17% of the target population) were not vaccinated with DTP3 in 2020 compared with 19.0 million (14%) in 2019. Children who did not receive the first DTP dose (DTP1) by age 12 months (zero-dose children) accounted for 95% of the increased number. Among those who did not receive DTP3 in 2020, approximately 17.1 million (75%) were zero-dose children. Global coverage decreased in 2020 compared with 2019 estimates for the completed series of Haemophilus influenzae type b (Hib), hepatitis B vaccine (HepB), human papillomavirus vaccine (HPV), and rubella-containing vaccine (RCV). Full recovery from COVID-19-associated disruptions will require targeted, context-specific strategies to identify and catch up zero-dose and undervaccinated children, introduce interventions to minimize missed vaccinations, monitor coverage, and respond to program setbacks (3).
2020 年,世界卫生大会批准了《免疫议程 2030》(IA2030),该议程旨在降低全生命周期内由疫苗可预防疾病导致的发病率和死亡率。(1)本报告更新了之前的报告,(2)介绍了截至 2020 年的全球、区域和国家疫苗接种覆盖率估计数和趋势。与 2019 年相比,2020 年(新冠疫情开始时)首次和第三剂白喉、破伤风和无细胞百日咳疫苗(DTaP)接种率、未接种和未全程接种疫苗儿童数量的变化,描述了疫苗接种覆盖率的变化。全球 DTaP 第三剂(DTP3)和脊髓灰质炎疫苗(Pol3)覆盖率从 2019 年的 86%降至 2020 年的 83%。同样,含麻疹疫苗(MCV1)第一剂接种率从 2019 年的 86%降至 2020 年的 84%。上一次 DTP3 覆盖率达到 2020 年水平是在 2009 年,MCV1 和 Pol3 则是在 2014 年。2020 年,全球有 2270 万儿童(目标人群的 17%)未接种 DTP3,而 2019 年为 1900 万(14%)。12 月龄未接种第一剂 DTP(零剂次儿童)的儿童占增加人数的 95%。在 2020 年未接种 DTP3 的儿童中,约有 1710 万(75%)为零剂次儿童。(3)与 2019 年的估计数相比,2020 年全球覆盖率下降的疫苗包括流感嗜血杆菌(Hib)、乙型肝炎疫苗(HepB)、人乳头瘤病毒疫苗(HPV)和含风疹疫苗(RCV)。从与新冠疫情相关的干扰中全面恢复需要采取有针对性的、具体情况具体分析的策略,以发现和赶上零剂次和未全程接种疫苗的儿童,引入干预措施以尽量减少错过接种,监测覆盖率并应对计划挫折。