在法国西北部发现德尔塔克戎 XD 重组严重急性呼吸综合征冠状病毒 2 的传播和循环证据。
Evidence of Transmission and Circulation of Deltacron XD Recombinant Severe Acute Respiratory Syndrome Coronavirus 2 in Northwest France.
机构信息
Laboratory of Virology, Normandie University, Université de Rouen Normandie, Université de Caen Normandie, Inserm Unité Mixte de Recherche 1311 Dynamique Microbienne associée aux infections Urinaires et Respiratoires, Centre Hospitalier Universitaire Rouen, Rouen, France.
Regional Office, Santé publique France, Rouen, France.
出版信息
Clin Infect Dis. 2022 Nov 14;75(10):1841-1844. doi: 10.1093/cid/ciac360.
Abstract
In February 2022, samples collected in northwest France showed discordant molecular results. After virological and epidemiological investigations, 17 cases of Deltacron XD recombinant severe acute respiratory syndrome coronavirus 2 were confirmed by sequencing or suspected due to epidemiological links, showing evidence of an extended transmission event and circulation of this form, with low clinical severity.
摘要
2022 年 2 月，在法国西北部采集的样本显示出分子结果不一致。经过病毒学和流行病学调查，通过测序确认了 17 例德尔塔克戎 XD 重组严重急性呼吸综合征冠状病毒 2 病例，或由于流行病学联系而疑似病例，表明这种形式的传播事件和传播具有持续性，且临床严重程度较低。
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本文引用的文献
1
Increased household transmission and immune escape of the SARS-CoV-2 Omicron compared to Delta variants.
Nat Commun. 2022 Sep 29;13(1):5706. doi: 10.1038/s41467-022-33233-9.
2
First cases of Omicron in France are exhibiting mild symptoms, November 2021-January 2022.
Infect Dis Now. 2022 May;52(3):160-164. doi: 10.1016/j.idnow.2022.02.003. Epub 2022 Feb 12.
3
A dynamic nomenclature proposal for SARS-CoV-2 lineages to assist genomic epidemiology.
Nat Microbiol. 2020 Nov;5(11):1403-1407. doi: 10.1038/s41564-020-0770-5. Epub 2020 Jul 15.
4
A new coronavirus associated with human respiratory disease in China.
Nature. 2020 Mar;579(7798):265-269. doi: 10.1038/s41586-020-2008-3. Epub 2020 Feb 3.
5
Nextstrain: real-time tracking of pathogen evolution.
Bioinformatics. 2018 Dec 1;34(23):4121-4123. doi: 10.1093/bioinformatics/bty407.
6
MEGA X: Molecular Evolutionary Genetics Analysis across Computing Platforms.
Mol Biol Evol. 2018 Jun 1;35(6):1547-1549. doi: 10.1093/molbev/msy096.
7
CONFIDENCE LIMITS ON PHYLOGENIES: AN APPROACH USING THE BOOTSTRAP.
Evolution. 1985 Jul;39(4):783-791. doi: 10.1111/j.1558-5646.1985.tb00420.x.
8
Epidemiology, Genetic Recombination, and Pathogenesis of Coronaviruses.
Trends Microbiol. 2016 Jun;24(6):490-502. doi: 10.1016/j.tim.2016.03.003. Epub 2016 Mar 21.
9
Genomic Analysis of 15 Human Coronaviruses OC43 (HCoV-OC43s) Circulating in France from 2001 to 2013 Reveals a High Intra-Specific Diversity with New Recombinant Genotypes.
Viruses. 2015 May 7;7(5):2358-77. doi: 10.3390/v7052358.
10
Coronavirus HKU1 and other coronavirus infections in Hong Kong.
J Clin Microbiol. 2006 Jun;44(6):2063-71. doi: 10.1128/JCM.02614-05.
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