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MRE11 mobilizes CGAS and drives ZBP1-dependent necroptosis.

作者信息

Beltrán-Visiedo Manuel, Balachandran Siddharth, Galluzzi Lorenzo

机构信息

Department of Radiation Oncology, Weill Cornell Medicine, New York, NY, USA.

Center for Immunology, Fox Chase Cancer Center, Philadelphia, PA, USA.

出版信息

Cell Res. 2024 Jul;34(7):477-478. doi: 10.1038/s41422-024-00939-y.

Abstract
摘要

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本文引用的文献

1
MRE11 liberates cGAS from nucleosome sequestration during tumorigenesis.
Nature. 2024 Jan;625(7995):585-592. doi: 10.1038/s41586-023-06889-6. Epub 2024 Jan 10.
2
Z-form nucleic acid-binding protein 1 (ZBP1) as a sensor of viral and cellular Z-RNAs: walking the razor's edge.
Curr Opin Immunol. 2023 Aug;83:102347. doi: 10.1016/j.coi.2023.102347. Epub 2023 Jun 3.
3
The DNA Damage Response and Inflammation in Cancer.
Cancer Discov. 2023 Jul 7;13(7):1521-1545. doi: 10.1158/2159-8290.CD-22-1220.
4
ADAR1 masks the cancer immunotherapeutic promise of ZBP1-driven necroptosis.
Nature. 2022 Jun;606(7914):594-602. doi: 10.1038/s41586-022-04753-7. Epub 2022 May 25.
5
The cGAS-STING pathway as a therapeutic target in inflammatory diseases.
Nat Rev Immunol. 2021 Sep;21(9):548-569. doi: 10.1038/s41577-021-00524-z. Epub 2021 Apr 8.
6
Structural basis for the inhibition of cGAS by nucleosomes.
Science. 2020 Oct 23;370(6515):455-458. doi: 10.1126/science.abd0237. Epub 2020 Sep 10.
7
Mitochondrial DNA drives abscopal responses to radiation that are inhibited by autophagy.
Nat Immunol. 2020 Oct;21(10):1160-1171. doi: 10.1038/s41590-020-0751-0. Epub 2020 Aug 3.
8
The Cytoplasmic DNA Sensor cGAS Promotes Mitotic Cell Death.
Cell. 2019 Jul 11;178(2):302-315.e23. doi: 10.1016/j.cell.2019.05.035.
9
Cytosolic DNA Sensing in Organismal Tumor Control.
Cancer Cell. 2018 Sep 10;34(3):361-378. doi: 10.1016/j.ccell.2018.05.013. Epub 2018 Jun 28.
10
DNA damage sensor MRE11 recognizes cytosolic double-stranded DNA and induces type I interferon by regulating STING trafficking.
Proc Natl Acad Sci U S A. 2013 Feb 19;110(8):2969-74. doi: 10.1073/pnas.1222694110. Epub 2013 Feb 6.

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