El Oirdi Mohamed
Department of Life Sciences, College of Science, King Faisal University, Al Ahsa 31982, Saudi Arabia.
Department of Basic Sciences, Preparatory Year, King Faisal University, Al Ahsa 31982, Saudi Arabia.
Pharmaceuticals (Basel). 2024 May 27;17(6):692. doi: 10.3390/ph17060692.
There are a wide variety of phytochemicals collectively known as polyphenols. Their structural diversity results in a broad range of characteristics and biological effects. Polyphenols can be found in a variety of foods and drinks, including fruits, cereals, tea, and coffee. Studies both in vitro and in vivo, as well as clinical trials, have shown that they possess potent antioxidant activities, numerous therapeutic effects, and health advantages. Dietary polyphenols have demonstrated the potential to prevent many health problems, including obesity, atherosclerosis, high blood sugar, diabetes, hypertension, cancer, and neurological diseases. In this paper, the protective effects of polyphenols and the mechanisms behind them are investigated in detail, citing the most recent available literature. This review aims to provide a comprehensive overview of the current knowledge on the role of polyphenols in preventing and managing chronic diseases. The cited publications are derived from in vitro, in vivo, and human-based studies and clinical trials. A more complete understanding of these naturally occurring metabolites will pave the way for the development of novel polyphenol-rich diet and drug development programs. This, in turn, provides further evidence of their health benefits.
有各种各样的植物化学物质,统称为多酚。它们的结构多样性导致了广泛的特性和生物学效应。多酚存在于各种食物和饮料中,包括水果、谷物、茶和咖啡。体外和体内研究以及临床试验表明,它们具有强大的抗氧化活性、多种治疗作用和健康益处。膳食多酚已显示出预防许多健康问题的潜力,包括肥胖、动脉粥样硬化、高血糖、糖尿病、高血压、癌症和神经疾病。在本文中,我们引用最新的文献详细研究了多酚的保护作用及其背后的机制。这篇综述旨在全面概述目前关于多酚在预防和管理慢性病中作用的知识。引用的出版物来自体外、体内和基于人体的研究以及临床试验。对这些天然存在的代谢物有更全面的了解将为开发富含多酚的新型饮食和药物开发计划铺平道路。这反过来又进一步证明了它们对健康的益处。