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比较病理学委员会促进了犬类和人类癌症患者之间知识的转化。

Comparative pathology boards facilitate the translation of knowledge between canine and human cancer patients.

作者信息

Beck Jessica A, Mazcko Christina, Belluco Sara, Bitar Mireille, Brat Daniel, Bush Jonathan W, Chkheidze Rati, Corps Kara N, Frank Chad, Giannini Caterina, Horbinski Craig, Huse Jason T, Koehler Jennifer W, Miller Andrew D, Miller C Ryan, O'Sullivan M Gerard, Phillips Joanna J, Rissi Daniel R, Schott Courtney R, Stemmer-Rachamimov Anat, Yip Stephen, LeBlanc Amy K

机构信息

Comparative Oncology Program, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.

Université de Lyon, VetAgro Sup, UPSP 2021.A104 ICE 'Interactions Cellules Environnement', Axe Cancérologie, Lyon, France.

出版信息

Brain Pathol. 2025 Sep;35(5):e70013. doi: 10.1111/bpa.70013. Epub 2025 May 5.

Abstract

Comparative pathology boards bring together anatomic pathologists with expertise in canine and human histology to identify shared features, including immune or TME components, tumor subtypes, or prognostic tissue biomarkers. This article summarizes feedback to improve future initiatives and enhance the translational relevance of comparative oncology for human patients.

摘要

比较病理学委员会汇聚了在犬类和人类组织学方面具有专业知识的解剖病理学家,以识别共同特征,包括免疫或肿瘤微环境成分、肿瘤亚型或预后组织生物标志物。本文总结了相关反馈,以改进未来的举措,并增强比较肿瘤学对人类患者的转化相关性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bda7/12352920/4a3d276374d7/BPA-35-e70013-g001.jpg

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