超越单一靶点：利用钠通道的简并性实现骨关节炎镇痛
Beyond single targets: leveraging degeneracy in sodium channels for osteoarthritis analgesia.
作者信息
Perez-Miller Samantha, Khanna Rajesh
机构信息
Department of Pharmacology and Therapeutics, College of Medicine, University of Florida, Gainesville, FL, USA.
Center for Advanced Pain Therapeutics and Research (CAPToR), College of Medicine, University of Florida, Gainesville, FL, USA.
出版信息
Pain Rep. 2025 May 27;10(4):e1289. doi: 10.1097/PR9.0000000000001289. eCollection 2025 Aug.
Abstract
Shin SM, Itson-Zoske B, Xu H, Xiang H, Fan F, Hogan QH, Yu H. Sensory neuron-specific block of multifaceted sodium channels mitigates neuropathic pain behaviors of osteoarthritis. Pain Rep 2025. DOI: 10.1097/PR9.0000000000001288.
摘要
申SM、伊特森 - 佐斯克B、徐H、向H、范F、霍根QH、于H。多方面钠通道的感觉神经元特异性阻断减轻骨关节炎的神经性疼痛行为。疼痛报告2025年。DOI: 10.1097/PR9.0000000000001288
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