Zhang Minghe, Li Jian, Fan Lianhui, Liu Hongtao
General Hospital of Northern Theater Command, Shenyang, China.
J Med Case Rep. 2025 Aug 16;19(1):409. doi: 10.1186/s13256-025-05478-7.
Abdominal pain caused by diabetic ketoacidosis is uncommon and can easily be misdiagnosed as abdominal pain caused by ureteral stones.This case highlights the importance of distinguishing between these etiologies, particularly in patients with diabetes, as delayed recognition of diabetic ketoacidosis can result in life-threatening complications. The novelty lies in emphasizing the diagnostic challenges and the necessity for clinicians to consider diabetic ketoacidosis even when imaging suggests alternative causes.
This case report describes a 59-year-old Han female patient who was admitted to the hospital for "generalized abdominal pain without obvious cause for 3 days" and was diagnosed with left ureteral stones. Initial imaging revealed a left ureteral stone and hydronephrosis, prompting ureteral stent placement. Despite antispasmodics, analgesics, and stent insertion, her pain persisted. Diabetic ketoacidosis was subsequently confirmed through laboratory tests. Following comprehensive systemic treatment, metabolic parameters were successfully normalized, and the patient recovered and was discharged from the hospital.
The mechanisms and treatment approaches for abdominal pain caused by ketoacidosis and ureteral stones differ significantly. Clinicians treating abdominal pain in patients with a history of diabetes should consider the possibility of ketoacidosis-induced abdominal pain, especially when conventional antispasmodic and analgesic treatments for ureteral stones are ineffective. Prompt identification of diabetic ketoacidosis via comprehensive clinical assessment and laboratory investigations is crucial to avoid delays in appropriate treatment. Enhanced recognition of the overlapping symptoms between diabetic ketoacidosis and ureteral stones can minimize diagnostic errors and lead to better patient outcomes.
糖尿病酮症酸中毒引起的腹痛并不常见,很容易被误诊为输尿管结石引起的腹痛。该病例突出了区分这些病因的重要性,尤其是对于糖尿病患者,因为延迟识别糖尿病酮症酸中毒可能导致危及生命的并发症。其新颖之处在于强调了诊断挑战以及临床医生即使在影像学提示其他病因时也有必要考虑糖尿病酮症酸中毒。
本病例报告描述了一名59岁的汉族女性患者,因“无明显原因的全腹痛3天”入院,被诊断为左输尿管结石。初始影像学检查发现左输尿管结石和肾积水,遂行输尿管支架置入术。尽管使用了解痉药、镇痛药并插入了支架,她的疼痛仍持续存在。随后通过实验室检查确诊为糖尿病酮症酸中毒。经过全面的系统治疗,代谢参数成功恢复正常,患者康复出院。
酮症酸中毒和输尿管结石引起的腹痛的机制和治疗方法有显著差异。治疗有糖尿病病史患者腹痛的临床医生应考虑酮症酸中毒引起腹痛的可能性,尤其是在针对输尿管结石的传统解痉和镇痛治疗无效时。通过全面的临床评估和实验室检查及时识别糖尿病酮症酸中毒对于避免适当治疗的延迟至关重要。加强对糖尿病酮症酸中毒和输尿管结石重叠症状的认识可以最大限度地减少诊断错误并带来更好的患者预后。