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美国国家农业图书馆的i5k工作区——实现节肢动物基因组数据的访问、可视化和管理。

The i5k Workspace@NAL--enabling genomic data access, visualization and curation of arthropod genomes.

作者信息

Poelchau Monica, Childers Christopher, Moore Gary, Tsavatapalli Vijaya, Evans Jay, Lee Chien-Yueh, Lin Han, Lin Jun-Wei, Hackett Kevin

机构信息

National Agricultural Library, Beltsville, MD 20705, USA

National Agricultural Library, Beltsville, MD 20705, USA.

出版信息

Nucleic Acids Res. 2015 Jan;43(Database issue):D714-9. doi: 10.1093/nar/gku983. Epub 2014 Oct 20.

Abstract

The 5000 arthropod genomes initiative (i5k) has tasked itself with coordinating the sequencing of 5000 insect or related arthropod genomes. The resulting influx of data, mostly from small research groups or communities with little bioinformatics experience, will require visualization, dissemination and curation, preferably from a centralized platform. The National Agricultural Library (NAL) has implemented the i5k Workspace@NAL (http://i5k.nal.usda.gov/) to help meet the i5k initiative's genome hosting needs. Any i5k member is encouraged to contact the i5k Workspace with their genome project details. Once submitted, new content will be accessible via organism pages, genome browsers and BLAST search engines, which are implemented via the open-source Tripal framework, a web interface for the underlying Chado database schema. We also implement the Web Apollo software for groups that choose to curate gene models. New content will add to the existing body of 35 arthropod species, which include species relevant for many aspects of arthropod genomic research, including agriculture, invasion biology, systematics, ecology and evolution, and developmental research.

摘要

5000节肢动物基因组计划(i5k)的任务是协调对5000种昆虫或相关节肢动物基因组进行测序。由此产生的大量数据大多来自生物信息学经验较少的小型研究团队或群体,这些数据需要进行可视化、传播和管理,最好是通过一个集中式平台来完成。美国国家农业图书馆(NAL)已经实施了i5k Workspace@NAL(http://i5k.nal.usda.gov/),以帮助满足i5k计划的基因组托管需求。鼓励任何i5k成员将其基因组项目详情告知i5k Workspace。提交后,新内容将通过生物体页面、基因组浏览器和BLAST搜索引擎进行访问,这些都是通过开源的Tripal框架实现的,Tripal框架是底层Chado数据库模式的一个网络界面。我们还为选择管理基因模型的团队实施了Web Apollo软件。新内容将添加到现有的35种节肢动物物种库中,这些物种包括与节肢动物基因组研究诸多方面相关的物种,如农业、入侵生物学、系统学、生态学和进化以及发育研究等。

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