Zečić Aleksandra, Dhondt Ineke, Braeckman Bart P
Department of Biology, Laboratory of Aging Physiology and Molecular Evolution, Ghent University, 9000 Ghent, Belgium.
Genes Nutr. 2019 May 6;14:15. doi: 10.1186/s12263-019-0637-7. eCollection 2019.
Animals require sufficient intake of a variety of nutrients to support their development, somatic maintenance and reproduction. An adequate diet provides cell building blocks, chemical energy to drive cellular processes and essential nutrients that cannot be synthesised by the animal, or at least not in the required amounts. Dietary requirements of nematodes, including have been extensively studied with the major aim to develop a chemically defined axenic medium that would support their growth and reproduction. At the same time, these studies helped elucidating important aspects of nutrition-related biochemistry and metabolism as well as the establishment of as a powerful model in studying evolutionarily conserved pathways, and the influence of the diet on health.
动物需要摄入足够的各种营养物质来支持其发育、身体维持和繁殖。充足的饮食提供细胞构建块、驱动细胞过程的化学能量以及动物无法合成或至少无法以所需量合成的必需营养物质。线虫的饮食需求,包括……已经得到了广泛研究,主要目的是开发一种化学成分明确的无菌培养基,以支持它们的生长和繁殖。与此同时,这些研究有助于阐明营养相关生物化学和代谢的重要方面,以及将……确立为研究进化保守途径以及饮食对健康影响的强大模型。