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行为风险因素与健康预期寿命:来自英格兰和美国两项老龄化纵向研究的证据。

Behavioural risk factors and healthy life expectancy: evidence from two longitudinal studies of ageing in England and the US.

机构信息

Department of Epidemiology and Public Health, University College London, London, UK.

Department of Behavioural Science and Health, University College London, London, UK.

出版信息

Sci Rep. 2020 Apr 24;10(1):6955. doi: 10.1038/s41598-020-63843-6.

Abstract

We examined whether the co-occurrence of four behavioural risk factors (alcohol consumption, smoking, physical inactivity and obesity) is associated with disability-free and chronic disease-free life expectancy similarly in two longitudinal studies of ageing in England and the United States. Data were from 17,351 individuals aged 50+ from the US Health and Retirement Study (HRS) and, 10,388 from the English Longitudinal Study of Ageing (ELSA), from 2002 to 2013. Disability-free life expectancy was estimated using repeat measures of limitations with instrumental activities and activities of daily living and, chronic disease-free life expectancy was based on chronic health conditions. Multistate life table models were used to estimate sex-specific health expectancy at the ages of 50, 60 and 70. In both countries and at all ages, there was a clear gradient towards shorter health expectancy with increasing number of behavioural risk factors. Compared to people with 2+ behavioural risk factors, in both countries, those with no behavioural risk factors could expect to live up to 11 years longer without disability and, up to 12 years longer without chronic conditions. Individual and co-occurring behavioural risk factors were strongly associated with shorter healthy life expectancy in both countries, attesting to the robustness of the contribution of lifestyle factors on health expectancy.

摘要

我们在英国和美国的两项老龄化纵向研究中,检验了四种行为风险因素(饮酒、吸烟、身体活动不足和肥胖)同时出现是否与无残疾和无慢性病预期寿命具有相似的相关性。数据来自美国健康与退休研究(HRS)的 17351 名 50 岁以上的个体和 2002 年至 2013 年来自英国老龄化纵向研究(ELSA)的 10388 名个体。无残疾预期寿命是通过对工具性日常生活活动和日常活动的限制进行重复测量来估计的,无慢性病预期寿命则基于慢性健康状况。多状态生命表模型用于估计 50、60 和 70 岁时的性别特异性健康预期寿命。在这两个国家,所有年龄段的人,随着行为风险因素数量的增加,健康预期寿命明显缩短。与有 2 个以上行为风险因素的人相比,在这两个国家,没有行为风险因素的人无残疾预期寿命可延长 11 年以上,无慢性病预期寿命可延长 12 年以上。个体和同时出现的行为风险因素与这两个国家的健康预期寿命缩短密切相关,证明了生活方式因素对健康预期寿命的贡献是稳健的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c5e/7181761/3b8da83cefa6/41598_2020_63843_Fig1_HTML.jpg

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