Khalaf Mohammad K, Rosen Heather E, Mitra Sudeshna, Neki Kazuyuki, Mbugua Leah Watetu, Hyder Adnan A, Paichadze Nino
Department of Global Health, Milken Institute School of Public Health, The George Washington University, Washington, DC, United States.
Global Road Safety Facility, World Bank, Washington, DC, United States.
JMIR Res Protoc. 2023 Feb 1;12:e40985. doi: 10.2196/40985.
Road traffic injuries (RTIs) are a leading cause of death and unintentional injuries globally. They claim 1.35 million lives and produce up to 50 million injuries each year, causing a major drain on health systems. Despite this high burden, there is a lack of robust data on the long-term consequences of RTIs, specifically the level of disability experienced by many survivors and its impact on their everyday lives.
This study aims to characterize RTIs, disability level, and related consequences affecting adult road traffic crash survivors in 5 low- and middle-income countries (LMICs). In addition, this study estimates the role of demographic and crash- and treatment-related factors in predicting adverse outcomes and disability as well as examining the disability level among patients with RTIs, likelihood of return to normal life, and the environmental factors that may influence these outcomes after discharge from the hospital.
This prospective observational study was conducted at selected hospitals in Bangladesh, Cambodia, Ethiopia, Mexico, and Zambia. The study sample included all adult patients with RTIs admitted to the hospital for at least 24 hours. Consecutive sampling was performed until the minimum required sample size of 400 was reached for each participating country. Data were collected from patients or their caregivers using a hospital-based surveillance tool administered at the participating sites as well as a telephone-based follow-up instrument administered 1, 3, and 6 months after discharge. Descriptive analysis and multivariate models will be used to estimate the contribution of a range of factors in predicting adverse outcomes, disability, and return to normal life.
Enrollment began in June 2021 and was completed in April 2022. Follow-up data collection ended in September 2022. Data analysis is currently underway, with results expected for publication in mid-2023. Expected results include estimates of disability among patients with RTIs as well as identifying the predictors of adverse outcomes, disability, and the likelihood of return to normal life.
Research findings will help better understand the long-term burden of disability from RTIs in the 5 LMICs and the challenges facing survivors of road traffic crashes. They will be used to inform interventions aimed at improving the health care, social, physical, and policy conditions in LMICs that can facilitate recovery and rehabilitation for patients with RTIs, reduce the burden of disability, and enhance their participation in society.
INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): DERR1-10.2196/40985.
道路交通伤害(RTIs)是全球死亡和意外伤害的主要原因。它们每年夺去135万人的生命,造成多达5000万人受伤,给卫生系统带来巨大负担。尽管负担如此沉重,但缺乏关于道路交通伤害长期后果的有力数据,特别是许多幸存者的残疾程度及其对日常生活的影响。
本研究旨在描述5个低收入和中等收入国家(LMICs)中成年道路交通碰撞幸存者的道路交通伤害、残疾程度及相关后果。此外,本研究估计人口统计学、碰撞及治疗相关因素在预测不良结局和残疾方面的作用,同时研究道路交通伤害患者的残疾程度、恢复正常生活的可能性,以及出院后可能影响这些结局的环境因素。
这项前瞻性观察性研究在孟加拉国、柬埔寨、埃塞俄比亚、墨西哥和赞比亚的选定医院进行。研究样本包括所有因道路交通伤害入院至少24小时的成年患者。进行连续抽样,直到每个参与国家达到至少400例的最小所需样本量。使用参与地点实施的基于医院的监测工具以及出院后1个月、3个月和6个月实施的基于电话的随访工具,从患者或其护理人员处收集数据。将使用描述性分析和多变量模型来估计一系列因素在预测不良结局、残疾和恢复正常生活方面的作用。
入组于2021年6月开始,2022年4月完成。随访数据收集于2022年9月结束。目前正在进行数据分析,预计结果将于2023年年中发表。预期结果包括对道路交通伤害患者残疾情况的估计,以及确定不良结局、残疾和恢复正常生活可能性的预测因素。
研究结果将有助于更好地了解5个低收入和中等收入国家道路交通伤害导致的长期残疾负担以及道路交通碰撞幸存者面临的挑战。这些结果将用于为旨在改善低收入和中等收入国家医疗保健、社会、身体和政策条件的干预措施提供信息,从而促进道路交通伤害患者的康复,减轻残疾负担,并增强他们对社会的参与度。
国际注册报告识别码(IRRID):DERR1-10.2196/40985。