Abbas Sagheer, Asif Muhammad, Rehman Abdur, Alharbi Meshal, Khan Muhammad Adnan, Elmitwally Nouh
Department of Computer Science, Prince Mohammad Bin Fahd University, Al-Khobar, KSA.
Department of Computer Science, Education University Lahore, Attock Campus, Pakistan.
Heliyon. 2024 Aug 23;10(17):e36743. doi: 10.1016/j.heliyon.2024.e36743. eCollection 2024 Sep 15.
This review article offers a comprehensive analysis of current developments in the application of machine learning for cancer diagnostic systems. The effectiveness of machine learning approaches has become evident in improving the accuracy and speed of cancer detection, addressing the complexities of large and intricate medical datasets. This review aims to evaluate modern machine learning techniques employed in cancer diagnostics, covering various algorithms, including supervised and unsupervised learning, as well as deep learning and federated learning methodologies. Data acquisition and preprocessing methods for different types of data, such as imaging, genomics, and clinical records, are discussed. The paper also examines feature extraction and selection techniques specific to cancer diagnosis. Model training, evaluation metrics, and performance comparison methods are explored. Additionally, the review provides insights into the applications of machine learning in various cancer types and discusses challenges related to dataset limitations, model interpretability, multi-omics integration, and ethical considerations. The emerging field of explainable artificial intelligence (XAI) in cancer diagnosis is highlighted, emphasizing specific XAI techniques proposed to improve cancer diagnostics. These techniques include interactive visualization of model decisions and feature importance analysis tailored for enhanced clinical interpretation, aiming to enhance both diagnostic accuracy and transparency in medical decision-making. The paper concludes by outlining future directions, including personalized medicine, federated learning, deep learning advancements, and ethical considerations. This review aims to guide researchers, clinicians, and policymakers in the development of efficient and interpretable machine learning-based cancer diagnostic systems.
这篇综述文章全面分析了机器学习在癌症诊断系统应用中的当前发展情况。机器学习方法在提高癌症检测的准确性和速度、应对大型复杂医学数据集的复杂性方面的有效性已变得显而易见。本综述旨在评估癌症诊断中使用的现代机器学习技术,涵盖各种算法,包括监督学习和无监督学习,以及深度学习和联邦学习方法。讨论了不同类型数据(如图像、基因组学和临床记录)的数据采集和预处理方法。本文还研究了癌症诊断特有的特征提取和选择技术。探讨了模型训练、评估指标和性能比较方法。此外,该综述深入探讨了机器学习在各种癌症类型中的应用,并讨论了与数据集限制、模型可解释性、多组学整合和伦理考量相关的挑战。强调了癌症诊断中可解释人工智能(XAI)这一新兴领域,着重介绍了为改进癌症诊断而提出的特定XAI技术。这些技术包括模型决策的交互式可视化和为增强临床解释而定制的特征重要性分析,旨在提高诊断准确性和医疗决策的透明度。文章最后概述了未来的方向,包括个性化医疗、联邦学习、深度学习进展和伦理考量。本综述旨在指导研究人员、临床医生和政策制定者开发高效且可解释的基于机器学习的癌症诊断系统。