Wu Chenkai, Smit Ellen, Xue Qian-Li, Odden Michelle C
School of Biological and Population Health Sciences, Oregon State University, Corvallis.
Department of Medicine, Division of Geriatric Medicine and Gerontology, School of Medicine, Johns Hopkins University, Baltimore, Maryland.
J Gerontol A Biol Sci Med Sci. 2017 Dec 12;73(1):102-108. doi: 10.1093/gerona/glx098.
Frailty is an age-related clinical syndrome of decreased resilience to stressors and is associated with numerous adverse outcomes. Although there is preponderance of literature on frailty in developed countries, limited investigations have been conducted in less developed regions including China-a country that has the world's largest aging population. We examined frailty prevalence in China by sociodemographics and geographic region, and investigated correlates of frailty.
Participants were 5,301 adults aged ≥60 years from the China Health and Retirement Longitudinal Study. Frailty was identified by the validated physical frailty phenotype (PFP) scale. We estimated frailty prevalence in the overall sample and by sociodemographics. We identified age-adjusted frailty prevalence by geographical region. Bivariate associations of frailty with health and function measures were evaluated by chi-squared test and analysis of variance.
We found 7.0% of adults aged 60 years or older were frail. Frailty is more prevalent at advanced ages, among women, and persons with low education. Age-adjusted frailty prevalence ranged from 3.3% in the Southeast and the Northeast to 9.1% in the Northwest, and was more than 1.5 times higher in rural versus urban areas. Frail versus nonfrail persons had higher prevalence of comorbidities, falls, disability, and functional limitation.
We demonstrated the utility of the PFP scale in identifying frail Chinese elders, and found substantial sociodemographic and regional disparities in frailty prevalence. The PFP scale may be incorporated into clinical practice in China to identify the most vulnerable elders to reduce morbidity, prevent disability, and enable more efficient use of health care resources.
衰弱是一种与年龄相关的临床综合征,对应激源的恢复力下降,并与众多不良后果相关。尽管发达国家有大量关于衰弱的文献,但在包括中国(拥有世界上最大老年人口的国家)在内的欠发达地区,相关调查有限。我们按社会人口统计学特征和地理区域研究了中国的衰弱患病率,并调查了衰弱的相关因素。
参与者为来自中国健康与养老追踪调查的5301名年龄≥60岁的成年人。通过经过验证的身体衰弱表型(PFP)量表来识别衰弱。我们估计了总体样本以及按社会人口统计学特征划分的衰弱患病率。我们确定了按地理区域调整年龄后的衰弱患病率。通过卡方检验和方差分析评估衰弱与健康及功能指标的双变量关联。
我们发现60岁及以上的成年人中有7.0%衰弱。衰弱在高龄人群、女性和低教育程度人群中更为普遍。按年龄调整后的衰弱患病率在东南部和东北部为3.3%,在西北部为9.1%,农村地区是城市地区的1.5倍多。衰弱者与非衰弱者相比,合并症、跌倒、残疾和功能受限的患病率更高。
我们证明了PFP量表在识别衰弱的中国老年人方面的效用,并发现衰弱患病率在社会人口统计学特征和区域方面存在显著差异。PFP量表可纳入中国的临床实践,以识别最脆弱的老年人,从而降低发病率、预防残疾,并更有效地利用医疗资源。