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[新型冠状病毒肺炎大流行对神经感染性疾病发生的影响]

[Influence of the COVID-19 pandemic on the occurrence of neurological infectious diseases].

作者信息

Völk Stefanie, Ködel Uwe, Pfister Hans-Walter, Klein Matthias

机构信息

Neurologische Klinik und Poliklinik, Klinikum der Universität München, LMU München, Marchioninistraße 15, 81377, München, Deutschland.

Zentrale Notaufnahme, Klinikum der Universität München, LMU München, München, Deutschland.

出版信息

Nervenarzt. 2023 Apr;94(4):278-286. doi: 10.1007/s00115-022-01420-0. Epub 2022 Dec 28.

Abstract

BACKGROUND

During the coronavirus disease 2019 (COVID-19) pandemic a wide range of hygiene measures were implemented to contain the spread of infections with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Besides a mitigation of SARS-CoV‑2, a decline in the number of other respiratory tract infections could be observed. Interestingly, the numbers for some infections of the central nervous system (CNS) decreased as well.

OBJECTIVE

This review article shows the development of important CNS infections in Germany during the COVID-19 pandemic.

MATERIAL AND METHOD

This article is based on relevant literature on the epidemiology of CNS infections during the COVID-19 pandemic up to autumn 2022.

RESULTS

During the COVID-19 pandemic the frequency of bacterial meningitis caused by Streptococcus pneumoniae, Neisseria meningitidis and Haemophilus influenzae significantly declined. The frequency of viral meningitis, particularly those caused by Enterovirus, decreased as well. In contrast, the number of patients suffering from tick-borne encephalitis significantly increased within the first year of the pandemic.

DISCUSSION

During the pandemic there was a decrease in cases of bacterial and viral meningitis, most likely due to the general containment strategies and social contact restrictions. The increase of infections transmitted by ticks could be a consequence of changed leisure activities during the pandemic.

摘要

背景

在2019年冠状病毒病(COVID-19)大流行期间,实施了广泛的卫生措施以遏制严重急性呼吸综合征冠状病毒2(SARS-CoV-2)感染的传播。除了SARS-CoV-2传播得到缓解外,还观察到其他呼吸道感染病例数量有所下降。有趣的是,一些中枢神经系统(CNS)感染的病例数也有所减少。

目的

这篇综述文章展示了德国在COVID-19大流行期间重要中枢神经系统感染的发展情况。

材料与方法

本文基于截至2022年秋季关于COVID-19大流行期间中枢神经系统感染流行病学的相关文献。

结果

在COVID-19大流行期间,由肺炎链球菌、脑膜炎奈瑟菌和流感嗜血杆菌引起的细菌性脑膜炎发病率显著下降。病毒性脑膜炎,尤其是由肠道病毒引起的病毒性脑膜炎发病率也有所下降。相比之下,在大流行的第一年,蜱传脑炎患者数量显著增加。

讨论

在大流行期间,细菌性和病毒性脑膜炎病例减少,很可能是由于总体防控策略和社会接触限制。蜱传播感染的增加可能是大流行期间休闲活动改变的结果。

相似文献

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本文引用的文献

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Decline in the number of patients with meningitis in German hospitals during the COVID-19 pandemic.
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Effect of high-dose sulfamethoxazole/trimethoprim and glucocorticoid use on hyperkalemic event: A retrospective observational study.
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