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1990 年至 2019 年期间,全球高血压心脏病负担的严重全球不平等现象持续存在:来自 2019 年全球疾病负担研究的结果。

Persistence of severe global inequalities in the burden of Hypertension Heart Disease from 1990 to 2019: findings from the global burden of disease study 2019.

机构信息

Innovation Research Institute of traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan, 250355, China.

Experimental Center, Shandong University of Traditional Chinese Medicine, Jinan, 250355, China.

出版信息

BMC Public Health. 2024 Jan 6;24(1):110. doi: 10.1186/s12889-023-17573-9.

Abstract

AIMS

Assessing the global burden and health inequalities of Hypertension Heart Disease (HHD) during the period from 1990 to 2019.

METHODS

Secondary analysis of the Global Burden of Disease (GBD) study in 2019, focusing on the burden of diseases, injuries, and risk factors worldwide. Disability-Adjusted Life Years (DALYs) data related to HHD are extracted from the 2019 GBD. Inequality Slope Index (SII) and Concentration Index are calculated to assess health inequalities across regions and countries.

RESULTS

The total DALYs for HHD reached 21.51 million, demonstrating a substantial increase of 54.25% compared to the figures recorded in 1990, while the age-standardized DALY rates per 100,000 population for HHD in 2019 showed a notable decline to 268.19 (95% UI 204.57, 298.07), reflecting a significant decrease of 26.4% compared to the rates observed in 1990. The DALYs rate of hypertensive heart disease increases with age. Countries with moderate SDI accounted for 38.72% of the global burden of HHD in terms of DALYs. The highest age-standardized DALY rates (per 100,000) are predominantly concentrated in underdeveloped areas. In 1990 and 2019, the SII (per 100,000 population) for DALYs were - 121.6398 (95% CI -187.3729 to -55.90684) and - 1.592634 (95% CI -53.11027 to 49.925) respectively. The significant decline suggests a reduction in the inequality of age-standardized burden of HHD between high-income and low-income countries during this period.

CONCLUSION

The unequal prevalence of HHD across different populations can hinder the achievement of the "health for all" objective. Persistent disparities in HHD have been observed globally over the past thirty years. It is crucial to prioritize efforts towards reducing avoidable health inequalities associated with hypertension-related heart disease, particularly in low-income and middle-income countries.

摘要

目的

评估 1990 年至 2019 年期间高血压心脏病(HHD)的全球负担和健康不平等状况。

方法

对 2019 年全球疾病负担(GBD)研究进行二次分析,重点关注全球疾病、伤害和危险因素的负担。从 2019 年 GBD 中提取与 HHD 相关的残疾调整生命年(DALY)数据。计算不平等斜率指数(SII)和集中指数,以评估区域和国家间的健康不平等情况。

结果

HHD 的总 DALY 达到 2151 万,与 1990 年相比增长了 54.25%,而 2019 年 HHD 的每 10 万人年龄标准化 DALY 率显著下降至 268.19(95%UI 204.57,298.07),表明与 1990 年相比下降了 26.4%。高血压性心脏病的 DALY 率随年龄增长而增加。中等 SDI 的国家占 HHD 全球负担的 38.72%(按 DALY 计算)。年龄标准化 DALY 率最高(每 10 万人)主要集中在欠发达地区。1990 年和 2019 年,DALY 的 SII(每 10 万人)分别为-121.6398(95%CI-187.3729 至-55.90684)和-1.592634(95%CI-53.11027 至 49.925)。这一显著下降表明,在此期间,高收入和低收入国家之间高血压性心脏病年龄标准化负担的不平等程度有所降低。

结论

不同人群中 HHD 的患病率不平等可能会阻碍实现“人人健康”的目标。在过去三十年中,全球范围内一直存在 HHD 的持续不平等现象。优先努力减少与高血压相关的心脏病相关的可避免的健康不平等现象至关重要,特别是在低收入和中等收入国家。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4bdb/10771693/6f8d92c846dd/12889_2023_17573_Fig1_HTML.jpg

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